Biologist François Jacob, who won the 1965 Nobel prize for medicine, died at the age of 92.
Christopher Voigt and his students at MIT have developed in E. coli the most complex synthetic cellular circuit ever built.
Physicists from the Curie Institute, France, explored the relative impact of the mechanical pressure induced by dividing cells in biological tissues.
Figuring out how life first started may seem like it should be simple—after all, life is everywhere on Earth. But the search is really far more complicated.
OpenMod will bring essential software building blocks to develop multiscale models for the Virtual Physiological Human.
Another publicly funded experiment involving genetically engineered crops faces possible destruction
An appeal from scientists at the publicly funded Rothamsted Research.
By measuring the rate of protein production in bacteria, a team at University of California, San Francisco (UCSF) discovered that slight genetic alterations could have a dramatic effect. This was true even for seemingly insignificant genetic changes known as “silent mutations,” which swap out a single DNA letter without changing the ultimate gene product. To their surprise, the scientists found these changes can slow the protein production process to one-tenth of its normal speed or less.
Wherever there are bacteria (digestive tracts, contaminated water,...) you will find a group of virus called bacteriophages.
Two leading manufacturers of DNA sequencing instruments announce that they would introduce new machines this year capable of sequencing an entire human genome in a single day for a cost of $1,000 per genome.
Insulin resistance is the harbinger of metabolic syndrome.
Mozambique, like many poor countries, has a high prevalence of vitamin A deficiency, which can erode the immune system and cause blindness. Pregnant woman and young children in low-income countries are often hit the hardest, according to the WHO, and 600,000 children are estimated to die from a lack of vitamin A each year.
At the end of this month, the world’s population will reach 7 billions; 1 billion are hungry, and 1 billion more are malnourished. In the next decades, there will be more humans. Limited land and water, costly energy for fertilizer, and climate change will ensure that more of them are hungry. Science and technology can contribute greatly to the solution. Why then is Europe regulating one part of the solution- GM (genetically modified) crops- as if they are a hazard?
One of the goals of computational biology is to predict the complete high-order structure of a protein from its amino acid sequence. Often reasonably good structures can be produced by modeling a new protein according to an already-known structure of a homologous protein, one with a similar sequence and presumably a similar structure. However, these structures can be inaccurate, and obviously this method will not work if no homologous structure is known.
Delebecque and coworkers describe in Science the design and construction of self-assembling RNA scaffolds that spatially organize enzymes in bacterial cells.
Andreas Engel, Professor for Structural Biology and former Chairman of the Biozentrum, retired from service to the Biozentrum and became Professor emeritus in October 2010. On February 11th, 2011, the Biozentrum bade farewell to its long standing member and remarkable researcher with a scientific symposium in his honor.
A bacterial chromosome is so long that it must be highly compacted and folded to stand within the cellular space. Genetic studies coupled with fluorescence microscopy showed that it is well organized into isolated domains. These domains also move with order when the chromosome is duplicated and the two new chromosomes are separated each in one half the dividing cell.
The December 2010 issue contains several papers dedicated to bacterial cell division. The journal cover highlights a 3D model of the bacterial division machinery (the divisome) created with the LifeExplorer tool in collaboration with F.-X. Barre and N. Dubarry.
Researchers at the Institute of Genetics and Molecular and Cell Biology (CNRS / University of Strasbourg / Inserm) have determined the first atomic structure of an eukaryotic ribosome (yeast ribosome).