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La Machinerie de la Vie
Qu'est-ce qui rend le sida si dangereux ? En quoi sa structure fait de la grippe un virus inventif ? A quelle partie d'une bactérie une molécule antibiotique s'attaque-t-elle ? Quels sont les mécanismes moléculaires à l'œuvre dans la mort programmée des cellules humaines ? Pourquoi le renouvellement des cellules peut-il amener au cancer ? Le livre "La Machinerie de La Vie" par David Goodsell répond à ces questions et émerveillera toute personne qui souhaite voir et ainsi comprendre comment les molécules de la vie s'organisent pour faire fonctionner les cellules. Le texte est très concis et l'auteur est un pionnier dans l'illustration scientifique réaliste. La grande originalité du livre sont les 70 représentations artistiques qui replacent les très nombreuses molécules nécessaires à la vie dans l'espace intérieur si réduit des cellules et des virus.
The Pink Army : It is time for a revolution
The challenge of the Pink Army cooperative : Creating faster and cheaper individualized therapies for breast cancer based on synthetic biology through open-source development.
'Simple' bacterium shows surprising complexity
A study published in Science shows that the inner workings of a supposedly simple bacterial cell have turned out to be much more sophisticated than expected. To obtain a detailed view of the functional and spatial organisation of the proteome, the study uses a large panel of experimental technics: genomic analysis, affinity chromatography and mass spectrometry, single-particle electron microscopy and electron tomography.
Mapping the human microbiome
A study reported November 5 in Science provides one of the most thorough whole-body maps to date of the estimated 100 trillion individual microbes the body harbors inside and out. It offers a basis for understanding what roles microbes have in both maintaining good health and causing diseases. Among other conclusions, the researchers found that the microbiome is highly personalized and seems to remain fairly constant over time.
SSB, a dynamic protector of single-stranded DNA
Researchers report that a single-stranded DNA-binding protein (SSB) in the bacterium E. coli, once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth along single-stranded DNA, gradually allowing other proteins to repair, recombine or replicate the strands.
How bacteria can sense temperature
Temperature is one of the most crucial environmental signals sensed by pathogens to adjust expression of their virulence factors and host survival programs after entry from a cold external environment into a warm-blooded host. Thermo-induced structural changes in bent or supercoiled DNA or mRNA secondary structures are frequently used to modulate virulence gene transcription or translation.
La Machinerie de la Vie
De la recherche à la création d'entreprise, l'exemple des agro-bio-technologies
