Events http://www.fourmentinguilbert.org Site Events daily 1 2009-12-28T16:17:26Z Design, optimization and control in systems and synthetic biology http://www.fourmentinguilbert.org/postings/design-optimization-and-control-in-systems-and-synthetic-biology The main aim of quantitative systems biology is to obtain a quantitative understanding of the functionning of biological systems at the cellular and tissue levels. To reach this goal, significant research efforts have been made to combine quantitative modeling approaches and state-of-the-art live-cell observation methods, notably via the joint use of time-lapse microscopy, reporter genes techniques and microfluidics. Although mainly developped with the objective of helping with better understanding the complex functionning of biological system, this approach has also been applied to two other problems. Firstly, it plays a central role to support the rational design and optimization of engineered biological systems in synthetic biology. Secondly, it has been instrumental to the development of novel methods for the control of intracellular processes at the cell level.

This workshop focuses on these two recent research directions. Its main aim is to gather during two days, leading international scientists who significantly contributed to these domains. Topics of particular interest include long-term imaging of cellular processes, microfluidics, synthetic biology, quantitative modeling of biomolecular processes, and control theory applied to biological systems.

keywords: quantitative biology, microfluidics and single cell biology, biological noise, control and optimization, synthetic biology, deterministic and stochastic modeling.

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